张博

副教授、 博士生导师、 皇家化学会会员
Journal of Separation Science 副主编
邮箱： bozhang@xmu.edu.cn
网站： https://bozhang.xmu.edu.cn

个人简历：
威尼斯615vip游戏化学系 副教授 （2009年11月至今）
Associate Professor, Xiamen University (2009.11-now)
英国帝国理工学院化学系 博士后 （2007年-2009年）
PostDoc, Imperial College London, UK (2007-2009)
英国约克大学化学系 博士 （2002年-2007年）
PhD, The University of York, UK (2002-2007)
中国科学院大连化学物理研究所国家色谱中心 研究助理 （1999年-2002年）
Research Assistant, National Chromatographic Center, Dalian Institute of Chemical Physics, Chinese Academy of Science (1999-2002) 
吉林大学化学系 学士 （1995年-1999年）
BSc, Jilin University, China (1995-1999)

研究兴趣：
色谱与分离科学；微流控芯片与先进制造；蛋白质组学与生物医学分析；液相分离-质谱联用技术 Chromatography and Separation Science; Microfluidics and Advanced Fabrication; Proteomics and Biomedical Analysis; Liquid Phase Separation Hyphenation with Mass Spectrometry

近期主要代表论著：

1. 1.  A  Microfluidic-Fabricated Rod Sprayer for Nanoelectrospray Mass  Spectrometry. Juxing Zeng, Kaiyue Sun, Shiyi Chen, Xin Zhang, Xiaofei  Wang, Bo Zhang*. Analytical Chemistry, 2024, 96, 3989-3993.

2. 2. Polarity-extended  liquid chromatography-triple quadrupole mass spectrometry for simultaneous  hydrophilic and hydrophobic metabolite analysis. Rui Guo, Qisheng Zhong,  Jiaqi Liu, Peiming Bai, Zongpeng Wang, Jieling Kou, Peijie Chen, Jie Zhang, Bo Zhang*. Analytica Chimica Acta, 2023, 1277, 341655.

3. 3. Recent advancements in nanoelectrospray ionization interface and coupled devices. Shiyi Chen, Juxing Zeng, Zhendian Zhang, Bolin Xu, Bo Zhang*. Journal of Chromatography Open, 2022, 2, 100064.

4. 4. Mass Fabrication of Capillary Columns Based on Centrifugal Packing. Ya Liu, Hanrong Wen,  Shiyi Chen, Xiaojuan Wang, Xudong Zhu, Lianzhong Luo, Xiaofei Wang, Bo Zhang*. Analytical Chemistry, 2022, 94, 8126-8131.

5. 5. Segmented Microfluidics-Based Packing Technology for Chromatographic Columns. Xiaofei Wang, Jue Zhu, Chenyuhu Yang, Fei Qin, Bo Zhang*. Analytical Chemistry, 2021, 93, 8450-8458.

6. 6. Direct Infusion ICP‑qMS of Lined-up Single-Cell Using an Oil-Free Passive Microfluidic System.      Yang Zhou, Zhangqian Chen, Juxing Zeng, Jiaxuan Zhang, Danxia Yu, Bo Zhang*, Xiaowen Yan, Limin Yang, Qiuquan Wang*. Analytical Chemistry, 2020, 92, 5286-5293.

7. 7. Performance of nanoflow liquid chromatography using core-shell particles: A comparison study. Ya Liu, Kaiyue Sun, Chuyi Shao, Xiaohui Shi, Juxing Zeng, Rui Guo, Bo Zhang*. Journal of Chromatography A, 2021, 1648, 462218.

8. 8. Separation and screening of antioxidant peptides  from scomberomorus niphonius based on nanoflow liquid chromatography. Yaru Xue, Rui Guo, Bo Zhang*.  Chinese Journal of Chromatography, 2020, 38, 1431-1439.

9. 9. Towards a high peak capacity of 130 using nanoflow hydrophilic interaction liquid chromatography. Ya Liu, Xiaofei  Wang, Zhangqian Chen, Derek Hecheng Liang, Kaiyue Sun, Shanqing Huang, Jue Zhu, Xiaohui Shi, Juxing Zeng, Qiuquan Wang, Bo Zhang*. Analytica Chimica Acta, 2019, 1062, 147-155.

10. 10. Microscale Sample Transfer Technology for  Capillary Two Dimensional Liquid Chromatography. Ya Liu, Bo Zhang*. Chinese Journal of Analytical Chemistry, 2019,  47, 1803-1808.

11. 11. Metabolomics Study of Rat Urine with Long Term  Arsenic Exposure. Xiaofei Wang, Yunwang Shen, Jue Zhu, Bo Zhang*. Chinese Journal of Analytical Chemistry, 2019, 47, 1045-1053.

12. 12. Research and Application Progress of Micellar Electrokinetic  Chromatography in Separation of Proteins. Fan Gao, Xiaofei Wang, Bo Zhang*.  Chinese Journal of Analytical Chemistry, 2019, 47, 805-813.

13. 13. Microfluidic Array Liquid Chromatography: A Proof  of Principle Study. Zhuoheng Zhou, Ya Liu, Bo Zhang*. Chinese Journal of   Analytical Chemistry, 2019, 47, 500-507.

14. 14. Performance of Long Packed Nanoflow Liquid Chromatographic Columns in Proteomics Analysis. Xiaofei  Wang,  Fei Qin, Rui Guo, Bo Zhang*. Chinese Journal of Analytical Chemistry, 2019, 47, 388-393.

15. 15. Recent advances in hyphenation nanoflow liquid phase separation with inductively coupled plasma mass spectrometry. Fangfang Ding, Jue Zhu, Rui Guo, Bo Zhang*. Chinese Journal of Chromatography, 2019, 37,  132-142.

16. 16. Multicolumn technologies in chromatographic analysis. Xiaofei Wang, Kaiyue Sun, Bo Zhang*. Chinese Journal of  Chromatography, 2019, 37, 123-131.

17. 17. Electrochromatographic behavior of core-shell particles:  A comparison study. Lijun Yang, Lingjia Xu, Rui Guo, Tianyu Gao, Haoxing Guo, Yue Yu, Jijian Lv, Qiuquan Wang, Bo Zhang*.  Analytica Chimica Acta, 2018, 1033, 205-212.

18. 18. Two dimensional separations of human urinary protein digest using a droplet-interfaced platform. Linquan Ye, Xin Wang, Jing Han, Fan Gao, Lingjia Xu, Zhiliang Xiao, Peiming Bai, Qiuquan Wang, Bo Zhang*. Analytica Chimica Acta, 2015,  863, 86-94.

19. 19. Towards high peak capacity separations in normal pressure nanoflow liquid chromatography using meter long packed capillary columns. Jing Han, Linquan Ye, Lingjia Xu, Zhuoheng Zhou, Fan Gao, Zhiliang Xiao, Qiuquan Wang, Bo Zhang*.  Analytica Chimica Acta, 2014, 852, 267-273.

20. 20. A comparison study of  in-column and on-column detection for electrochromatography. Qier Zhang,      Lingjia Xu, Zhuoheng Zhou, Lijun Yang, Qiuquan Wang, Bo Zhang*. Journal of  Chromatography A, 2014, 1362, 225-230.

21. 21. Fabrication and investigation of electrochromatographic columns with a simplex configuration. Qing Liu, Lijun Yang, Qiuquan Wang, Bo Zhang*. Journal of Chromatography A, 2014, 1349, 90-95.

22. 22. Toward rapid preparation of capillary columns for electrochromatography use. Qing Liu, Lin Wang,      Zhuoheng Zhou, Qiuquan Wang, Lijuan Yan, Bo Zhang*. Electrophoresis 2014, 35, 836-839.

23. 23. A “plug-and-use” approach towards facile fabrication of capillary columns for high performance nanoflow liquid chromatography. Zhiliang Xiao, Lin Wang, Ya Liu, Qiuquan Wang, Bo Zhang*. Journal of Chromatography A, 2014, 1325, 109-114.

24. 24. Capillary electrophoresis-based immobilized enzyme reactor using particle-packing technique. Lina Liu, Bo Zhang, Qian Zhang, Yanhong Shi, Liping Guo, Li  Yang*. Journal of Chromatography A, 2014, 1352, 80-86.

25. 25. A chemical “hub”  for absolute quantification of a targeted protein: orthogonal integration of elemental and molecular mass spectrometry. Xiaowen Yan, Zhaoxin Li, Yong Liang, Limin Yang, Bo Zhang, Qiuquan Wang*. Chemical Communications, 2014, 50, 6578-6581.

26. 26. EphA2 enhances the  proliferation and invasion ability of LNCaP prostate cancer cells. Peijie Chen, Yan Huang, Bo Zhang, Qiuquan Wang, Peiming Bai*. Oncology Letters,  2014, 8, 41-46.

27. 27. Click chemistry mediated Eu-tagging: activity-based specific quantification and simultaneous  activity evaluation of CYP3A4 using Eu-153 species-unspecific isotope  dilution inductively coupled plasma mass spectrometry. Yong Liang, Xiaowen Yan, Zhaoxin Li, Limin Yang, Bo Zhang, Qiuquan Wang*. Analytical  Chemistry, 2014, 86, 3688-3692.

28. 28. Performance of single  particle fritted capillary columns in electrochromatography. Bo Zhang*,  Qing Liu, Lijun Yang, Qiuquan Wang. Journal of Chromatography A, 2013,  1272, 136-140.

29. 29. Droplet microfluidics  based microseparation systems. Zhiliang Xiao, Menglei Niu, Bo Zhang*. Journal of Separation Science, 2012, 35, 1284-1293.

30. 30. Sensitive ionization of  non-volatile analytes using protein solutions as spray liquid in  desorption electrospray ionization mass spectrometry. Zhiqiang Zhu, Jing Han, Yan Zhang, Yafei Zhou, Ning Xu, Bo Zhang, Haiwei Gu, Huanwen Chen*.  Rapid Communications in Mass Spectrometry, 2012, 26, 2770-2776.

31. 31. Integrin-targeted trifunctional probe for cancer cells: a "seeing and counting" approach. Zhubao Zhang, Qiang Luo, Xiaowen Yan, Zhaoxin Li, Yacui Luo,  Limin Yang, Bo Zhang, Haifeng Chen, Qiuquan Wang*. Analytical Chemistry,  2012, 84, 8946-8951.

32. 32. Europium-labeled  activity-based probe through click chemistry: absolute serine protease  quantification using 153Eu isotope dilution ICP/MS. Xiaowen Yan, Yacui  Luo, Zhubao Zhang, Zhaoxin Li, Qiang Luo, Limin Yang, Bo Zhang, Haifeng  Chen, Peiming Bai, Qiuquan Wang*. Angew. Chem. Int. Ed. 2012, 51,  3358-3363.

33. 33. Droplet microfluidics: technologies and applications. Zhiliang Xiao, Bo Zhang*. Chinese Journal of Chromatography, 2011, 29, 949-956.

34. 34. Development of a  droplet-interfaced high performance liquid chromatography-capillary electrophoresis two dimensional separation platform. Linquan Ye, Qingshi Wu, Simin Dai, Zhiliang Xiao, Bo Zhang*. Chinese Journal of  Chromatography, 2011, 29, 857-861.

35. 35. Photocatalytical reduction of disulphide bonds in peptides on Ag-loaded nano-TiO₂  for subsequent derivatization and determination. Lijuan Wang, Xiaowen Yan,  Chunlai Xu, Zhiliang Xiao, Limin Yang, Bo Zhang, Qiuquan Wang*. Analyst,  2011, 136, 3602-3604.

36. 36. Electrically assisted capillary liquid chromatography using a silica monolithic column. Bo Zhang, Edmund T. Bergstrom, David M. Goodall*. Journal of Chromatography A, 2010, 1217, 2243-2247.

37. 37. Droplet-based compartmentalization of chemically separated components in two-dimensional separations. X. Z.  Niu, B. Zhang (co-first author), R. T. Marszalek, O. Ces, J. B. Edel, D. R. Klug and A. J. deMello*. Chem. Commun., 2009, 6159–6161.

38. 38. Capillary action liquid chromatography. Bo Zhang, Edmund T. Bergstrom, David M. Goodall*, Peter  Myers. Journal of Separation Science, 2009, 32, 1831-1837.

39. 39. Single-particle fritting  technology for capillary electrochromatography. Bo Zhang, Edmund T.  Bergstrom, David M. Goodall*, Peter Myers. Analytical Chemistry, 2007, 79,  9229-9233.

40. 40. Determination of alcohols  by high performance liquid chromatography with fluorimetric detection  after pre-column derivatisation with carbazole-9-N-acetic acid and chromatographic behaviour of alcoholic derivatives. Jinmao You, Bo Zhang,  Weibing Zhang, Pei Yang, Yukui Zhang*. Journal of Chromatography A, 2001,  909, 171-182.

41. 41. On line enrichment of  neutral solute in capillary electrochromatography. Weibing Zhang, Jun Zhu,  Jinmao You, Bo Zhang, Guichen Ping, Yukui Zhang*. Chinese Journal of  Analytical Chemistry, 2001, 29, 869-875.

42. 42. Study on on-column  concentration of ionic sample in capillary electrochromatography - model development and investigation. Weibing Zhang, Bo Zhang, Jun Zhu, Yukui  Zhang*. Acta Chimica Sinica, 2001, 59, 257-261.

43. 43. A new method for the  measurement of dead time in reversed phase high performance liquid chromatography. Bo Zhang, Qinghe Zhang, Yichu Shan, Weibing Zhang, Yukui Zhang*. Modern Scientific Instruments, 2000, 2, 26-27.